October 17, 2026
A rigorous exploration of serially spiro-fused cyclobutanes as three-dimensional drug scaffolds, covering ring strain energetics, synthetic routes, conformational entropy, and the strategic…
October 17, 2026
Planar molecules dominate screening libraries yet fail in the clinic. Discover how one-carbon insertion chemistry converts flat scaffolds into three-dimensional drug candidates…
October 17, 2026
Skeletal editing lets medicinal chemists swap a single carbon atom for nitrogen inside a proven molecular scaffold, altering binding, metabolism, and solubility…
September 3, 2026
Explore how skin volatile compounds and microbiome chemical signals determine mosquito species' biting preferences, revealing the organic chemistry behind personal mosquito attraction…
September 3, 2026
Explore the molecular innovations behind the 2026 ACS Green Chemistry Challenge Awards, where biocatalysis, atom economy, and degradation-by-design are redefining sustainable crop…
September 3, 2026
Discover how a new nickel-based catalyst cleaves lignin's stubborn ether bonds under mild conditions, transforming agricultural waste into valuable aromatic chemicals and…
September 3, 2026
Explore how skin chemistry and bacterial metabolites influence mosquito biting preferences through the lens of Class 11 organic chemistry, covering functional groups,…