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Least Significant and Most Significant Bit

For a binary representation of a number, the Least Significant Bit (LSB) is the binary 1s place or simply the rightmost bit.

The Most Significant Bit (MSB) is the highest-order place of the binary integer or the left-most bit.

Consider the binary number 10110010(178 in decimal form). Its LSB and MSB are shown below.

1 (MSB)0110010 (LSB)
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